Thermoanalytical Characterization of Pharmaceuticals
E. Marti, E. Kaisersberger, G. Kaiser, W.-Y. Ma
Selected example of drug substances and excipients are outlined in this workbook, which is based on thermoanalytical measurements using DSC, thermobalance, TG-FTIR, TG-DSC-MS and c-DTA.
Each substance is introduced by literature and pharmaceutical use. Special attention having been paid to the presentation of easily understandable experimental results. In addition, the collected experimental facts have been evaluated by different software programs. Routines have been applied for the determination melting points, enthalpy of fusion and crystallization, dehydration, purity, kinetic data, Gibbs free energy function, melting range and molten fraction. The importance of gas analysis by FTIR and mass spectrometry has been underlined. The results obtained with the performed investigation are brought into the context of thermodynamics, physical chemistry and solidstate or material sciences. www.ngb.netzsch.com
Netzsch-Geraetebau GmbH, Selb, Germany, Price Euro 48,57 (excl. VAT and shipping costs)
|
|
