Contributions by internationally renowned specialists in the field afford a detailed insight into single bioinformatics components and algorithmic methods. In addition, the state-of-the-art in bioinformatics is evaluated equally from a global view by introducing real application scenarios such as genome projects that require the use of whole set of bioninformatics tools. Directed to all those involved in the use of development of new bioinformatics tools this book will lead one step further on the way to rational drug design.