The info brochures published by Mediport Biotechnik, Berlin, cover data gained from extensive studies using perfused porcine organ systems in in vitro research.
These systems allow for the reliable prediction of feasibility in man already at early developmental stages in the evaluation of drug and medicinal product potentials. The brochures present general descriptions as well as examples of applications of the perfused organ systems. The content is part of a comprehensive database comprising studies conducted at Mediport Biotechnik in the process of standardizing the systems for the use in in vitro contract research. The isolated perfused heart has been used for the determination of drug impact on the QT interval, a distinct part of the ECG, which is indicative for potential cardiac arrhythmias. The perfused fore limb was used for transdermal resorption studies and for the assessment of medicinal products, such as needle-free injection systems and stents. The company provides the brochure for free on request.
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