PROCESS-3-2003

50 years of DNA!

One of the most important discoveries of the twentieth century was doubtless the double helix structure of DNA. Elucidated by Francis Crick and James Watson in 1953, it is the basis of modern molecular biology. Without it, Science would not have come so far in the development of new medicines and therapies against illness. Automated high-throughput procedures and the continually on-going development of computer analyses assist in the finding and analysis of the building blocks of life. Above all, however, in winning from them new knowledge on the effective treatment of illnesses.


, den 29. April 2003

The final version of the human genome was recently announced in Washington, Francis Collins, director of the US National Human Genome Project Institute, described this as the provisional last step in the comprehensive sequencing project. With the human genome decoded to 98.5% there is a great hope that it will be possible to successfully treat cancer, diabetes or cardio-vascular disease. Despite all of this knowledge, new illnesses that puzzle scientists and doctors continue to crop up. Have viruses declared war on man? The HIV virus is with certainty the most devastating one.

It has already taken the lives of millions of people, and is as yet still undefeated. And ever more new and modified viruses are being discovered and claim numerous victims, as shown by SARS (severe acute respiratory syndrome), the current example. Coronaviruses are believed to trigger this, but this is not yet proven. Are medicine and research reaching their limits? Probably not. Great sums are invested in research and development, and Europe has caught up considerably against the USA. Numbers substantiate this. In 2001, there were 1879 companies active in biotechnology in Europe. That is around 400 more than in the USA, and 16% more than in the previous year. The total turnover in Europe increased to 13.7 billion euro, 7.5 billion euro were invested in R&D. The market in Asia is also subject to great movement. According to the Helmut Kaiser Consultancy, the Chinese government will invest more than 150 billion euros in the new growth markets, i.e. in biotechnology, up to 2010.

However, such figures should not hide the fact that state aid and financing through venture capital companies no longer flow unimpeded, as they did three or four years ago. Insolvencies, company mergers, company take-overs and redundancies all characterized year 2002. For the upward trend in the biotechnolgy branch to continue, despite the momentary bad atmosphere in the worldwide economy, further investment and the fostering of competitiveness are necessities. Successful research and development,and their translation into innovative medicines, are the safeguards for the future of the international biotechnology and pharmaceutical industries. In spite of all the investments, whether and when a coup like that of Watson and Crick will be pulled off, is questionnable. Fact is, that 50 years ago a new era in thinking on the essentials and violability of life began.

 

-Rosemarie Asang-Soergel-


Thorsten Nick